Chromosomal aberration analysis for biological dose assessment 染色體畸變分析估計生物劑量
Structural chromosomal aberration 染色體結構畸變
Investigation on the rate of chromosomal aberrations of the workers in radiology department in liaocheng city in 2004年聊城市不同級別單位放射工作人員染色體畸變情況調查
Research on the relationship between occupational exposure to mixed benzene and chromosomal aberration of peripheral blood lymphocytes 職業性三苯接觸對人外周血淋巴細胞染色體結構的影響
Several studies have shown that so2 and its derivatives could induce chromosomal aberrations , sister chromatid exchanges and micronuclei in human blood lymphocyte , bone marrow cell in mice and chl 研究發現, so _ 2及其衍生物可引起人外周血淋巴細胞、小鼠骨髓細胞、中國倉鼠肺成纖維細胞等哺乳動物細胞的染色體畸變、姊妹染色單體交換及微核的形成。
The aglycone , steviol , exhibited greater acute toxicity than stevioside in hamsters but not in rats . steviol was clearly genotoxic after metabolic activation , inducing forward mutations in bacteria and gene mutations and chromosomal aberrations in lung fibroblasts of chinese hamsters 甜菊醇經過代謝活化后,基因毒性明顯,可引致細菌產生正向突變,以及使中國倉鼠的肺纖維原細胞產生基因突變和染色體變異。
The aglycone , steviol , exhibited greater acute toxicity than stevioside in hamsters but not in rats . steviol was clearly genotoxic after metabolic activation , inducing forward mutations in bacteria and gene mutations and chromosomal aberrations in lung fibroblasts of chinese hamsters 甜菊醇經過代謝活化后,基因毒性明顯,可引致細菌產生正向突變,以及使中國倉鼠的肺纖維原細胞產生基因突變和染色體變異。
Several kinds of herbicides treating together show an antagonistic action also exist , even tend to intensify . the results also indicate that the inductive effect was weakened when 2 - ethy - 4 - chloro sodium hydration operated with other herbicides . nc - 302d ( + ) can evidently increase the frequencies of numerical and structural chromosomal aberrations 除草劑精禾草克試驗組泥鰍染色體數目畸變率均有明顯上升,有的組甚至與對照組差異極顯著( p 0 . 01 ) ;各試驗組染色體結構畸變率與對照組差異均極顯著( p 0 . 01 ) 。
Monofunctional alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng ) is a widely spread environmental mutagen and carcinogen that targets dna and proteins to generate adducts . among the adducts , o6 - alkyl guanine is the predominant mutagenic lesion because of its mispairing properties , which can eventually lead to chromosomal aberrations , point mutations , and cell death . this lesion also appears to be involved in tumor initiation , particularly in gastric carcinogenesis 單功能烷化劑n -甲基- n -硝基- n -亞硝基胍( mnng )是一種在環境中廣泛存在的化學誘變劑和致癌劑,它能和dna及蛋白質等生物大分子形成加合物( adduct ) ,其引起的與突變有關的主要dna損傷類型是o ~ 6 -甲基鳥嘌呤,這種損傷與腫瘤尤其是胃癌的發生密切相關。